Does anyone have any experience using this combo?

Good bad or indifferent.

Does it play nicely with the Pixhawk? It says the 1280 ESC is optimized for the DJI A3 and N3 flight controllers.The ESC and the flight controllers communicate in real time, making instant intervention possible in the event of an abnormality. A back up throttle system* can automatically kick in if the primary throttle line is interrupted, minimizing accidents and increasing safety.

Some proprietary hocus pocus going on with it that may muddy up the water using with PH??

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