"Hi Dave,  
From the IO-Board's RST pin (top right as seen in pictures), it should go to the DTR pin on your FTDI board. I have no idea about the wire color, since my boards only have pin headers and I use my own wires."

"Hi Dave. Make sure you also connect the reset pin from FTDI to IO-Board, I couldn't make it work properly until I did that."

"Hi,
I also had a lot of issues with not being able to connect with bootloader.
For me it all got sorted out as soon as I've connected the Reset pin to my FTDI board.

As far as I can tell, as soon as the ioboard starts sending telemetry data or…"