ESC pass-through tuning with Pixhawk

I have a Pixhawk FC, and am going to buy new ESCs. I was reading about calibrating and tuning ESCs and it seems that pass-through is not possible with Pixhawk([1][2]). 

(i) Are there any alternative/ solution for this? I am not going to be able to change my FC.
(ii) Can, QGC calibrate/ tune ESC ?
(iii) Also, what is the difference between what is meant by calibrating, tuning and programming an ESC. Can some please explain?

I would be really grateful if someone could clarify the above for me.

Regards,
Ash!sh.

[1] https://discuss.px4.io/t/blheli-pass-thr...px4/3798/3
[2] https://github.com/ArduPilot/ardupilot/issues/5120

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